منابع مشابه
Messenger RNA in animal cells.
It is difficult to believe that only 2 years ago, the very existence of messenger RNAs in animal cells was doubtful, and no definitive example of an isolated and purified mRNA could be given. Since that time, the mRNAs for globin (from rabbit, man, mouse, duck, and guinea pig), lens crystallin (chick and cow), ovalbumin, myosin, and silk fibroin have been isolated and their identities confirmed...
متن کاملThe synthesis and processing of a nuclear RNA precursor to rat pregrowth hormone messenger RNA.
A recombinant DNA plasmid, pBR322-GH1, which contains about 80% of the sequences of rat pregrowth hormone (pGH) mRNA, allowed an analysis of nuclear RNA from GH3 cells for possible precursors of cytoplasmic pGH mRNA. A single 20-22S RNA SPECIES ABOUT 2-3 TIMes larger than pGH mRNA was detected in nuclear RNA from GH3 cells labeled for 5 min. with 3H-uridine. After longer label times a 12S RNA i...
متن کاملGrowth-related fluctuation in messenger RNA utilization in animal cells
Monkey fibroblasts maintained in culture regulate their levels of intracellular protein throughout the growth cycle by means of variations in the rate of protein biosynthesis. Cytoplasmic mRNA in stationary phase cells was compared to that in exponential phase cells. In stationary phase cells 56% of the cytoplasmic polyadenylated RNA was found in the 40--90S postpolysomal region of sucrose sedi...
متن کاملCell-free translation of paramyxovirus messenger RNA.
Polypeptides corresponding in electrophoretic mobility to virion polypeptides 1, 3, and 5 were made in a reticulocyte cell-free system to which 18S RNA from Sendai virus-infected cells was added. Immune precipitation was used to select relevant polypeptides from endogenous products. The cell-free product corresponding to virion polypeptide 3 (the nucleocapsid structure unit) was the most abunda...
متن کاملStructure and regulation of the messenger RNA coding for the corticotropin /beta-lipotropin precursor.
We cyclized pyruvyl-L-Ala-L-Hmb-L-Tyr-NH, by treatment with liquid H F and obtained cyclo(-Hy Ala-L-Ala-L-Hmb-LTyr-) (compound 4) in good yield instead of the desired cyclic peptide containing the AAla residue (Noda et al., 1980). The possibility of converting the HyAla residue in compound 4 into a AAla residue is now under investigation. (b) The relationship between structure and activity of A...
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ژورنال
عنوان ژورنال: Biochemical Journal
سال: 1981
ISSN: 0264-6021
DOI: 10.1042/bj1970001